Ischemia

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Ischemia o Ischaemia es un restriction in le copia sanguinari ad texito causante un carentia de oxygeno que es necessario pro le metabolismo cellular( ut sustener vivo le texito).[1]. Ischemia es generalmente causate per problemas con le vasso sanguinari, con resulta in damno o dysfunction de texito. Etiam ille significa anemia local in un parte dato de un corpore, a vices resultante de congestion ( sicut vasoconstriction, thrombosis or embolismo). Ischemia comprehende non solo le insufficientia de oxygeno, sed etiam le reducite disponibilitate de nutriente et inadequate subtraction del excremento metabolic. Ischemia pote esse partial(povre perfusion) o tal.


Ischemia or ischaemia is a restriction in blood supply to tissues, causing a shortage of oxygen that is needed for cellular metabolism (to keep tissue alive).[3] Ischemia is generally caused by problems with blood vessels, with resultant damage to or dysfunction of tissue. It also means local anemia in a given part of a body sometimes resulting from congestion (such as vasoconstriction, thrombosis or embolism). Ischemia comprises not only insufficiency of oxygen, but also reduced availability of nutrients and inadequate removal of metabolic wastes. Ischemia can be partial (poor perfusion) or total.

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Signs and symptoms[edit] Since oxygen is carried to tissues in the blood, insufficient blood supply causes tissue to become starved of oxygen. In the highly metabolically active tissues of the heart and brain, irreversible damage to tissues can occur in as little as 3–4 minutes at body temperature. The kidneys are also quickly damaged by loss of blood flow (renal ischemia). Tissues with slower metabolic rates may undergo irreversible damage after 20 minutes. Clinical manifestations of acute limb ischemia (which can be summarized as the "six P's") include pain, pallor, pulseless, paresthesia, paralysis, and poikilothermia.[4]

Without immediate intervention, ischemia may progress quickly to tissue necrosis and gangrene within a few hours. Paralysis is a very late sign of acute arterial ischemia and signals the death of nerves supplying the extremity.

  1. Merck & Co. Occlusive Peripheral Arterial Disease, The Merck Manual Home Health Handbook website, revised and updated March 2010. Retrieved March 4, 2012.