HMG-CoA reductase

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HMG-CoA reductase
instantia de: proteina
parte de: Hydroxymethylglutaryl-CoA reductase, metazoan[*], Hydroxymethylglutaryl-CoA reductase, class I/II, catalytic domain superfamily[*], Hydroxymethylglutaryl-CoA reductase, class I/II, substrate-binding domain superfamily[*], Hydroxymethylglutaryl-CoA reductase, N-terminal[*], Hydroxymethylglutaryl-CoA reductase, class I/II, NAD/NADP-binding domain superfamily[*], Eukaryotic Sterol Transporter[*]


Le HMG-CoA reductase (3-hydroxy-3-methyl-glutaryl-coenzyma A reductase, officialmente abbreviate HMGCR) es le enzyma (dependente de NADH,EC 1.1.1.88; dependente de NADPH, EC 1.1.1.34) que controla le velocitate del via del mevalonato, le via metabolic que produce cholesterol e altere isoprenoidos.