Fibromyalgia
Fibromyalgia es un medical condition characterisate per chronic diffuse dolor, fatiga, evelia non reposate, cognitive symptomas, dolor o crampos in basse abdomine, e depression.[1] Altere symptomas include insomnia[2] e hypersensibilitate.[3][4]
Affecta inter 2 e 4% del population, principalmente feminas.
Etiologia
[modificar | modificar fonte]Su causa non es cognite, ma non serea psychosomatic; poterea implicar genetic e ambiente factores[4], como stress psychologic, trauma o alcun infectiones.[4] Dolor resultarea de processos in central nervo systema e le condition es considerate como un "syndrome de sensibilisation central".[5][6]
Desde 2021, alcun studios suggera un origine autoimmun del desordine, implicante neutrophilos, cellulas implicate in le responsa immun innate e producente cytokinas responsibile de inflammation.[7][8]
Referentias
[modificar fonte]- ↑ Wolfe F, Clauw DJ, Fitzcharles MA, Goldenberg DL, Häuser W, Katz RL, Mease PJ, Russell AS, Russell IJ, Walitt B (December 2016). "2016 Revisions to the 2010/2011 fibromyalgia diagnostic criteria". Seminars in Arthritis and Rheumatism 46 (3): 319–329. doi:. PMID 27916278.
- ↑ Wu YL, Chang LY, Lee HC, Fang SC, Tsai PS (May 2017). "Sleep disturbances in fibromyalgia: A meta-analysis of case-control studies". Journal of Psychosomatic Research 96: 89–97. doi:. PMID 28545798.
- ↑ Häuser W, Sarzi-Puttini P, Fitzcharles MA (2019). "Fibromyalgia syndrome: under-, over- and misdiagnosis". Clinical and Experimental Rheumatology 37 (1 Suppl 116): 90–97. PMID 30747096.
- ↑ Arnold LM, Bennett RM, Crofford LJ, Dean LE, Clauw DJ, Goldenberg DL, Fitzcharles MA, Paiva ES, Staud R, Sarzi-Puttini P, Buskila D, Macfarlane GJ (June 2019). "AAPT Diagnostic Criteria for Fibromyalgia". The Journal of Pain 20 (6): 611–628. doi:. PMID 30453109.
- ↑ Clauw DJ (April 2014). "Fibromyalgia: a clinical review". JAMA 311 (15): 1547–1555. doi:. PMID 24737367.
- ↑ Mezhov V, Guymer E, Littlejohn G (December 2021). "Central sensitivity and fibromyalgia". Internal Medicine Journal 51 (12): 1990–1998. doi:. PMID 34139045.
- ↑ https://trustmyscience.com/fibromyalgie-origine-auto-immune-invasion-cellules-immunitaires/
- ↑ doi:10.1073/pnas.22116311